Hoodia California - H57 Hoodia P57

Molecule P57

admin — Wed, 03 Jan 2007 13:54:58 +0000

Why the P57 molecule is so famous worldwide?. Because it is the basic compound into the Hoodia Gordonii plant that creates apetite suppressing effects.

The name derives from being the 57th product developed by British pharmaceutical company Phytopharm wich have patent rights. The P57 molecule is only found in the Gordonii variety of Hoodia, and is the main element that launched Hoodia Gordonii as the world's greatest weight loss product on thesedays.

Firstly, it was the CSIR -a south african national body for industrial research- which studied the San tribes eating habits and discovered they lose weight. Then CSI sold the rights to Phytopharm, who patented the compound as P57.

Hoodia H57 and P57

Sat, 13 May 2006 21:13:03 +0000

Difference between Hoodia H57 and Hoodia P57

When you look for hoodia gordonii products, you may usually see some products with the mention of H57 or P57. Others are branded as Hoodia 57.

By that, the main question arises: Is there any difference between the so called H57 and P57??

The answer is no. In fact, H57 and P57 are a similar term to refer to Hoodia Gordonii.

Originally, Phytopharm, the english pharmaceutical company acquired the intellectual property rights developed over Hoodia gordonii from CSIR (South African Research and Development organisation).

Then, Phytopharm patented the product as P57 (the P is used in most of their patents). The patent rights were then transferred to Pfizer, which went back to Phytopharm after some time.

Now some technology rights have been licensed to food giant Unilever.

As a direct consequence of such situation some products and many news about hoodia gordonii , hoodia diet pills , hoodia cactus , south african hoodia and similars, used the term P57 into the product description and into the articles.

After some time, other companies coined the term H57 (acronymous for Hoodia 57) just to avoid the patented term from Phytopharm, and the term also became popular.

Some products offered into the market today are branded as H57 and many adevertisements or searches are performed using the term H57 or H57 Hoodia.

Just to avoid legal implications, the fact is that in both cases, P57 and H57 mean exactly the same: products made with Hoodia Gordonii.

Is P57 a Cardiac Glycoside?

Sat, 13 May 2006 21:02:38 +0000

MacLean DB and Luo LG, two researchers at the Division of Endocrinology, Hallett Center for Diabetes and Endocrinology, Brown Medical School, were intrigued by the fact that P57 is chemically similar to a class of plant-derived compounds called cardiac glycosides, of which the ones derived from various foxglove species (genus Digitalis) are the best known.

These powerful drugs increase the force of contraction of the heart muscle and help maintain normal heart rate and rhythm. A common side effect of the cardiac glycosides is loss of appetite.

Like many other drugs, cardiac glycosides act by interacting with specific receptor molecules embedded in the walls of our cells.

When stimulated by such interactions, these receptors (which are large, complex proteins that act as molecular channels) initiate a chain of events inside the cell, the net effect of which is the action attributed to the drug.

In the case of cardiac glycosides, the receptor molecule is called Na/K-ATPase. Its primary function is to regulate the flow of sodium ions (Na+) and potassium ions (K+) into and out of the cell through the molecular channel, using chemical energy provided by molecules of ATP (adenosine triphosphate).

How Hoodia is Tested in Labs? Liquid Chromatography

admin — Fri, 12 May 2006 00:00:00 +0000

The following is a document detailing the analysis method to determine the existence of appetite suppressant element P57 on hoodia gordonii plants.

P-068: DETERMINATION OF THE APPETITE SUPPRESSANT P57 IN HOODIA GORDONII PLANT EXTRACTS AND DIETARY SUPPLEMENTS BY LIQUID CHROMATOGRAPHY/ELECTROSPRAY IONIZATION MASS SPECTROMETRY (LC-MSD-TOF) AND LC-UV METHODS

Bharathi Avula1, Yan-Hong Wang 1, Rahul S. Pawar1, Yatin Shukla2, Brian T. Schaneberg3 and Ikhlas A. Khan1

1National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences; 2Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, MS 38677, USA; 3ChromaDex Analytics, Boulder, CO 80301 USA