Is there any USDA regulation for Hoodia before to enter the US market? YES.

As hoodia gordonii is a plant included in apendix II of CITES, an international convention to protect endangered species, the USDA has regulations to be complied with by the hoodia importers.

There are provisions for the hoodia being labeled upon arrival "Produced from Hoodia spp. material obtained through controlled harvesting and production in collaboration with the CITES Management Authorities of Botswana/Namibia/South Africa under agreement no. BS/NA/ZA xxxxxxx" (Annotation #9) to be permitted entry. However, no agreement yet exists between Botswana, Namibia, and South Africa of the type mentioned in annotiation #9 to the Appendices to CITES. This means that currently there is no exemption from the provisions of the Convention for trade in specimens of Hoodia spp. Because there is no exemption, trade in specimens of Hoodia spp. now requires the issuance of CITES permits or certificates.